Anti-BIMS/EL/L Rat Monoclonal Antibody [clone: 3C5]

Lieferant: ProSci
PRSI36-185EA 565 EUR
PRSI36-185
Anti-BIMS/EL/L Rat Monoclonal Antibody [clone: 3C5]
Antikörper
Bim belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the Bcl-2 protein family (BCL2, BCL2L1/BCL-X(L) and MCL1) and to act as an apoptotic activator, inducing apoptosis and anoikis. Several variants have been identified. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent.

ChIP: (1:200) Band shift assay: Competes with probe for NFAT binding. . Immunoprecipitation: (1:200) . Western Blot: (1:500-1:1000) . Optimal conditions must be determined individually for each application.

Type: Primary
Antigen: BIMS/EL/L
Clonality: Monoclonal
Clone: 3C5
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype: IgG2a kappa
Reactivity: Dog, Human, Monkey, Mouse, Rat
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