ɑ-Cyano-4-hydroxycinnamic acid ≥99,0% (durch HPLC) Matrixsubstanz für MALDI-MS, Supelco®

Lieferant: Merck
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Synonyme: 2-Cyano-3-(4-hydroxyphenyl)acrylic Acid, α-Cyano-4-hydroxycinnamic Acid, α-CHCA, CHCA

70990-1G-F
70990-1G-FEA 95.2 EUR
70990-1G-F
ɑ-Cyano-4-hydroxycinnamic acid ≥99,0% (durch HPLC) Matrixsubstanz für MALDI-MS, Supelco®
alpha-Cyano-4-hydroxycinnamic acid

α-Cyano-4-hydroxycinnamic acid (α-CHCA) is widely used as a matrix in order to facilitate ionization of peptides and proteins in a matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometer.


α-CHCA was used as matrix in improving the detection of low concentration protein digests on MALDI-TOF.

Formel: C₁₀H₇NO₃
Molecular Weight: 189,17 g/mol
Schmelzpunkt: 245…250 °C (Lit.)
MDL: MFCD00004204
CAS-Nummer: 28166-41-8

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Spezifikation Testergebnisse

Appearance (Color) Faint Yellow to Yellow
Appearance (Form) Powder or Crystals
Titration (T) NaOH 0.1M 99.0 - 101.0 %
Purity (HPLC area %) ≥ 99.0 %
Melting Point 245 - 250 C
Solubility (Color) Colorless to Faint Green-Yellow
Solubility (Turbidity) Clear
Solubility (Method) 0.1G IN 10 ml methanol
Proton NMR Spectrum Conforms to structure
Test by UV Spectroscopy Corresponds to requirements
Metal trace Analysis (ICP) Corresponds to requirements
BARIUM (ICP) ≤ 5 mg/kg
CALCIUM (ICP) ≤ 10 mg/kg
CADMIUM (ICP) ≤ 5 mg/kg
COBALT (ICP) ≤ 5 mg/kg
CHROMIUM (ICP) ≤ 5 mg/kg
COPPER (ICP) ≤ 5 mg/kg
POTASSIUM (ICP) ≤ 5 mg/kg
MAGNESIUM (ICP) ≤ 5 mg/kg
MANGANESE (ICP) ≤ 5 mg/kg
SODIUM (ICP) ≤ 10 mg/kg
NICKEL (ICP) ≤ 5 mg/kg
LEAD (ICP) ≤ 5 mg/kg
ZINC (ICP) ≤ 5 mg/kg
RECOMMENDED RETEST PERIOD 42 MONTHS

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