Tetradecyltrimethylammoniumbromid ≥99% (durch Titration), Calbiochem®, Sigma-Aldrich®
Lieferant: Merck Millipore Calbiochem
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Gefahr
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Synonyme:
Myristyltrimethylammoniumbromid
, TTAB
, Tetradoniumbromid
, Dynamin Inhibitor II
M-Clarity™ Qualitätsstufe = MQ100
The Dynamin Inhibitor II, MiTMAB, also referenced under CAS 1119-97-7, controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Membrane applications.
A cell-permeable cationic surfactant that reversibly inhibits dynamin GTPase activity (IC50 = 3.15 µM) by targeting the PH domain and interfering with phospholipid binding. Shown to block dynamin I-dependent SVE (synaptic vesicle endocytosis) in rat brain synaptosomes and dynamin II-dependent RME (receptor-mediated endocytosis) in non-neuronal HeLa, A431, and COS-7 cells. Inhibition is competitive with respect to PS and noncompetitive with respect to GTP.
Formel:
C₁₇H₃₈BrN Molecular Weight: 336,394 g/mol Lagertemperatur: Kühlschrank |
MDL:
MFCD00011770 CAS-Nummer: 1119-97-7 |
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