Staurosporine
Lieferant: Biotium
Synonyme:
(5S,6R,7R,9R)-6-Methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14-one, Antibiotic AM-2282
Staurosporine is a potent apoptosis inducer.
- Potent and cell-permeable inhibitor
- Induces apoptosis in human neuroblastoma cells
- Apoptosis in chick embryonic neurons
Staurosporine is a potent and cell-permeable inhibitor of a wide variety of protein kinases including protein kinase C (IC50 = 0.7 nM), protein kinase A (IC50 = 7 nM), and protein kinase G (IC50 = 8.5 nM). Staurosporine induces apoptosis in human neuroblastoma cells and chick embryonic neurons.
Formel:
C₂₈H₂₆N₄O₃ Molecular Weight: 466,541 g/mol |
MDL:
MFCD18252446 CAS-Nummer: 62996-74-1 |
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