cFMS Receptor Inhibitor IV ≥95% (durch HPLC), Calbiochem®, Sigma-Aldrich®
Lieferant: Merck Millipore Calbiochem
Synonyme:
5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide, CSF-1 Receptor Inhibitor IV
M-Clarity™ Qualitätsstufe = MQ100
The cFMS Receptor Inhibitor IV, also referenced under CAS 959626-45-0, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
General description
A cell-permeable furan carboxamide compound that acts as a potent, reversible, and ATP-competitive cFMS/CSF-1R inhibitor that blocks cFMS autophosphorylation both in CSF-1/M-CSF-stimulated HEK-293 cells (IC50 = 76 nM) and in cell-free in vitro kinase assays (IC50 = 17 nM).
Verpackung: Packaged under inert gas
Formel:
C₂₂H₂₆N₄O₂ Molecular Weight: 378,47 g/mol Lagertemperatur: Gefrierschrank |
MDL:
MFCD10568148 CAS-Nummer: 959626-45-0 |
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