JC-1 iodide salt ≥95% (durch HPLC), Calbiochem®
Lieferant: Merck Millipore Calbiochem
Synonyme:
JC-1
Verpackt unter Schutzgas
A cationic, fluorescent, carbocyanine dye that can be used as a ratiometric indicator of mitochondrial potential δΨm in cells, tissues, and isolated mitochondria.
Mitochondrial depolarisation is indicated by a decrease in the red/green fluorescence intensity ratio. The potential-sensitive color shift is due to concentration-dependent formation of red fluorescent J-aggregates. Ideal for detection of collapse of δΨm induced by uncouplers of mitochondrial respiration. JC-1 has also been used in a functional assay of multidrug-resistance cells and in apoptosis-related mitochondrial modifications.
Formel:
C₂₅H₂₇Cl₄IN₄ Molecular Weight: 652,23 g/mol Lagertemperatur: Gefrierschrank |
MDL:
MFCD00188475 CAS-Nummer: 47729-63-5 |
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