Sphingosine kinase inhibitor ≥98%, Millipore®
Lieferant: Merck Millipore Calbiochem
The sphingosine kinase inhibitor controls the biological activity of sphingosine kinase. This small molecule/inhibitor is primarily used for cell signaling applications.
- White solid
- Hygroscopic
A cell-permeable disubstituted thiazole compound that displays anti-tumor properties. Acts as a potent, substrate competitive, reversible, and highly specific inhibitor of sphingosine kinase. It does not affect the kinase activity of hERK2, hPI3K, or PKCα even at concentrations as high as 60 µM. Induces apoptosis in human cancer cells that express the drug transport proteins Pgp or MRP1 through inhibiting sphingosine-1-phosphate production.
Bitte beachten Storage temperature: Refrigerator
Lagertemperatur:
Kühlschrank |
CAS-Nummer:
1177741-83-1 |
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...