1,1-Dicyano-6-(4-N,N-dimethylaminophenyl)-1,3,5-hexatriene) (DCDAPH) fluoreszierender Farbstoff
Lieferant: Biotium
80030
80030.EA
319
EUR
80030.
1,1-Dicyano-6-(4-N,N-dimethylaminophenyl)-1,3,5-hexatriene) (DCDAPH) fluoreszierender Farbstoff
1,1-Dicyano-6-(4-N,N-dimethylaminophenyl)-1,3,5-hexatriene) (DCDAPH)
DCDAPH is a NIR fluorescent probe that has affinity for Aβ plaques/aggregates.
- Dark purple solid
- λEx/λEm = 597/665 nm (PBS)
- Store at -20°C and protect from light, especially in solution
DCDAPH (1,1-dicyano-6-(4-N,N-dimethylaminophenyl)-1,3,5-hexatriene) is a far-red fluorescent probe that has proved to have affinity to Aβ plaques. It has been used for fluorescent staining of brain sections, as well as in vivo detection of Aβ1-42 aggregates by small animal near-IR imaging1. DCDAPH has high affinity (Ki= 37 nM, Kd=27 nM) to Aβ1-42 aggregates.
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