Acridinorange (Chloridsalz)-Lösung 10 mg/mL in Wasser, Sigma-Aldrich®
Lieferant: SIGMA ALDRICH MICROSCOPY
Synonyme:
AO, C.I. 46005, 3,6-Bis(dimethylamino)acridine hydrochloride, Basic Orange 14, N,N,N’,N’-Tetramethyl-3,6-acridinediamine hydrochloride, 3,6-Acridinediamine, Acridine orange hydrochloride
Acridine Orange hydrochloride solution has been used to study autophagic cell death. It has also been used for the staining of chromosomes.
- hematology: suitable
- histology: suitable
Acridine Orange is a metachromatic dye which can stain DNA, RNA and acid glycosaminoglycans. At low concentration it intercalates into DNA and precipitates RNA. However, at high concentration it denatures and precipitates both RNA and DNA. Acridine Orange is also used to analyze autophagy. It goes into acidic organelles in a pH-dependent manner. At neutral pH, acridine orange gives a green fluorescence and in acidic conditions, it accumulates in the acidic organelle giving a bright red fluorescence.
Formel:
C₁₇H₁₉N₃·HCl·xH₂O Molecular Weight: 301,81 g/mol (anhy) Lagertemperatur: Raumtemperatur |
MDL:
MFCD00012660 CAS-Nummer: 65-61-2 |
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