Anti-APBB1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Lieferant: Bioss
BS-0110R-A647
BOSSBS-0110R-A647EA 893 EUR
BOSSBS-0110R-A647
Anti-APBB1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antikörper
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: APBB1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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