Anti-CLN8 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-11715R-A680
BOSSBS-11715R-A680EA 890 EUR
BOSSBS-11715R-A680
Anti-CLN8 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterised by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.

Type: Primary
Antigen: CLN8
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 201-286/286
Host: Rabbit
Isotype: IgG
Reactivity: Human, Rat
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