Anti-CLN8 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Lieferant: Bioss
BS-11715R-FITC
BOSSBS-11715R-FITCEA 893 EUR
BOSSBS-11715R-FITC
Anti-CLN8 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Antikörper
CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CLN8
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype:
Reactivity:
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