Anti-TMEM16C/Anoctamin 3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-12479R-A750
BOSSBS-12479R-A750EA 890 EUR
BOSSBS-12479R-A750
Anti-TMEM16C/Anoctamin 3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
TMEM16C is a 981 amino acid multi-pass membrane protein that is encoded by a gene which maps to chromosome 11. With approximately 135 million base pairs and 1400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumours, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Type: Primary
Antigen: TMEM16C/Anoctamin 3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 801-900/981
Host: Rabbit
Isotype: IgG
Reactivity:
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