Anti-DKK1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Lieferant: Bioss
BS-2162R-A555
BOSSBS-2162R-A555EA 901 EUR
BOSSBS-2162R-A555
Anti-DKK1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Antikörper
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: DKK1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Dog
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