Anti-DKK3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-2686R-A680
BOSSBS-2686R-A680EA 899 EUR
BOSSBS-2686R-A680
Anti-DKK3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
Antagonises canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Type: Primary
Antigen: DKK3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 31-130/350
Host: Rabbit
Isotype: IgG
Reactivity: Mouse; Rabbit
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