Anti-DAXX Rabbit Polyclonal Antibody (Cy3®)

Lieferant: Bioss
BS-5292R-CY3
BOSSBS-5292R-CY3EA 922 EUR
BOSSBS-5292R-CY3
Anti-DAXX Rabbit Polyclonal Antibody (Cy3®)
Antikörper
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED3 protease family. A novel DD containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx is a death domain containing important intermediate in the Fas mediated apoptosis. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N terminal kinase (JNK) pathway. It is widely expressed in fetal and adult human and mouse tissue, indicating its important function in Fas signaling pathways.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: DAXX
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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