Anti-Myosin 7a Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-7761R-A680
BOSSBS-7761R-A680EA 893 EUR
BOSSBS-7761R-A680
Anti-Myosin 7a Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organisation of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

Type: Primary
Antigen: Myosin 7a
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 851-950/2215
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse
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