Chrysin 97%, Sigma-Aldrich®
Lieferant: SIGMA ALDRICH MICROSCOPY
Synonyme:
5,7-Dihydroxy-2-phenyl-4H-chromen-4-on, 5,7-Dihydroxy-2-phenyl-4H-benzo[b]pyran-4-on, 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-on, 5,7-Dihydroxy-2-phenyl-4-benzopyron, 5,7-Dihydroxy-2-phenylchromen-4-on, 5,7-Dihydroxyflavon
M-Clarity™ Qualitätsstufe = MQ100
Chrysin has been used to study the effect of bioflavonoids on the inhibition of ATP synthase in Escherichia coli. It has been used to study the effect of Chrysin on eIF4E (eukaryotic translation initiation factor 4E) expression in AGS cell (human gastric carcinoma cell) line. It has been used to study the effect of chrysin on human ovarian cancer cells.
Chrysin is a flavonoid and an analog of apigenin. It inhibits aromatase and also suppresses human immunodeficiency virus (HIV) activation in models with latent infection. Chrysin exhibits anti-inflammatory and anti-oxidant effects. This molecule induces apoptosis in various cells, thereby exhibiting cancer chemopreventive activity. Chrysin can modulate the activity of GABAA (Type-A γ-aminobutyric acid) and GABAC receptors, it downregulates expression of PCNA (proliferating cell nuclear antigen), reduces activity of CDK2 (cyclin-dependent kinase 2) and CDK4 and induces p38-MAPK (mitogen-activated protein kinase) activation.
Formel:
C₁₅H₁₀O₄ Molecular Weight: 254,24 g/mol Siedepunkt: 429 °C (1013 hPa) Schmelzpunkt: 284…286 °C (Lit.) Lagertemperatur: Room Temperature |
MDL:
MFCD00006834 CAS-Nummer: 480-40-0 EINECS: 207-549-7 |
Spezifikation Testergebnisse
Appearance (Colour) | Faint yellow to yellow and faint beige to beige and faint brown to light brown |
Appearance (Form) | Powder |
Titration (Nt) Tbaoh 0.1M | 96.5 - 103.5 % |
Purity (HPLC Area %) | ≥96.5 % |
Solubility (Colour) | Yellow to Amber |
Solubility (Turbidity) | Clear to slightly hazy |
Solubility (Method) | 50Mg/Ml, Pyridin |
Infrared Spectrum | Conforms to Structure |
Wavelength (1) (Uv) | 344 - 352 Nm |
Molar Absorbancy Index (1) | ≥8000 |
Wavelength (2) (Uv) | 278 - 286 Nm |
Molar Absorbancy Index (2) | ≥22000 |
Wavelength (3) (Uv) | 259 - 267 Nm |
Molar Absorbancy Index (3) | ≥20000 |
Wavelength (4) (Uv) | 220 - 228 Nm |
Molar Absorbancy Index (4) | ≥27000 |
Uv Method | In 0.1N NaOH |
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