Chrysin 97%, Sigma-Aldrich®

Lieferant: SIGMA ALDRICH MICROSCOPY

Synonyme: 5,7-Dihydroxy-2-phenyl-4H-chromen-4-on, 5,7-Dihydroxy-2-phenyl-4H-benzo[b]pyran-4-on, 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-on, 5,7-Dihydroxy-2-phenyl-4-benzopyron, 5,7-Dihydroxy-2-phenylchromen-4-on, 5,7-Dihydroxyflavon

M-Clarity™ Qualitätsstufe = MQ100

C80105-25G
C80105-25GEA 205 EUR
C80105-25G
Chrysin 97%, Sigma-Aldrich®
Chrysin

Chrysin has been used to study the effect of bioflavonoids on the inhibition of ATP synthase in Escherichia coli. It has been used to study the effect of Chrysin on eIF4E (eukaryotic translation initiation factor 4E) expression in AGS cell (human gastric carcinoma cell) line. It has been used to study the effect of chrysin on human ovarian cancer cells.


Chrysin is a flavonoid and an analog of apigenin. It inhibits aromatase and also suppresses human immunodeficiency virus (HIV) activation in models with latent infection. Chrysin exhibits anti-inflammatory and anti-oxidant effects. This molecule induces apoptosis in various cells, thereby exhibiting cancer chemopreventive activity. Chrysin can modulate the activity of GABAA (Type-A γ-aminobutyric acid) and GABAC receptors, it downregulates expression of PCNA (proliferating cell nuclear antigen), reduces activity of CDK2 (cyclin-dependent kinase 2) and CDK4 and induces p38-MAPK (mitogen-activated protein kinase) activation.

Formel: C₁₅H₁₀O₄
Molecular Weight: 254,24 g/mol
Siedepunkt: 429 °C (1013 hPa)
Schmelzpunkt: 284…286 °C (Lit.)
Lagertemperatur: Room Temperature
MDL: MFCD00006834
CAS-Nummer: 480-40-0
EINECS: 207-549-7
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Spezifikation Testergebnisse

Appearance (Colour) Faint yellow to yellow and faint beige to beige and faint brown to light brown
Appearance (Form) Powder
Titration (Nt) Tbaoh 0.1M 96.5 - 103.5 %
Purity (HPLC Area %) ≥96.5 %
Solubility (Colour) Yellow to Amber
Solubility (Turbidity) Clear to slightly hazy
Solubility (Method) 50Mg/Ml, Pyridin
Infrared Spectrum Conforms to Structure
Wavelength (1) (Uv) 344 - 352 Nm
Molar Absorbancy Index (1) ≥8000
Wavelength (2) (Uv) 278 - 286 Nm
Molar Absorbancy Index (2) ≥22000
Wavelength (3) (Uv) 259 - 267 Nm
Molar Absorbancy Index (3) ≥20000
Wavelength (4) (Uv) 220 - 228 Nm
Molar Absorbancy Index (4) ≥27000
Uv Method In 0.1N NaOH

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