Transfection reagent, TransIT-VirusGEN® SELECT
Lieferant: MIRUS
Large scale virus production for preclinical and early phase clinical trials.
- Efficient DNA delivery for large-scale production of high-titer virus vectors
- Qualityt ested for performance, identity, sterility, endotoxin and mycoplasma
- Reliable with exceptional lot-to-lot consistency
- Flexibility with compatible with different virus production platforms and repeat filtration
- Animal origin free, a fully synthetic transfection reagent formulation
Efficient, high titer and large-scale virus vector manufacturing processes are necessary for production of virus vectors such as lentivirus and adeno-associated virus (AAV) for gene- and cell-based therapies. Additionally, raw or ancillary materials used for virus vector manufacturing must be carefully selected as part of a risk-based approach for the development of therapeutics. The TransIT-VirusGEN® SELECT transfection reagent addresses both needs by providing robust titers for lentivirus and AAV production and comprehensive quality documentation for researchers developing biotherapeutics for immunotherapy.
TransIT-VirusGEN® SELECT is identical in formulation to the TransIT-VirusGEN® transfection reagent, which was developed by screening lipid and polymer libraries to identify a reagent formulation that enhances delivery of virus packaging and transfer vectors to HEK 293 cells. Using a functional titer read-out, Mirus scientists identified this novel and defined transfection formulation that enables high titer lentivirus and AAV production in both adherent, serum-containing cultures, as well as serum free suspension HEK 293-derived cell types.
The streamlined virus generation workflows and culture format versatility make TransIT-VirusGEN® an ideal reagent for scientists utilizing a variety of virus platforms. With TransIT-VirusGEN® SELECT, researchers can expect the same reliable, scalable, and flexible performance of the TransIT-VirusGEN® transfection Reagent as they progress from discovery and development to clinical trials.
In addition to the Quality Control testing established for TransIT-VirusGEN® Transfection Reagent, the TransIT-VirusGEN® SELECT transfection reagent is further qualified with sterility, identity, mycoplasma and endotoxin assays per relevant USP guidelines.
Standards: Certificate of Origin: No Animal Derived Components.
Bestellinformation: TransIT-VirusGEN® SELECT Transfection Reagent is available as a 30 ml dispense.
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