PPM1B Human siRNA Oligo Duplex (Locus ID 5495)
Lieferant: OriGene
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways.
- Stability: One year from date of shipment when stored at −20 °C
- Quality control: Tested by ESI-MS
- Purity: HPLC purified
- UniProt ID: O75688
This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
Single siRNA duplex (10 nmol) can be ordered.
Number of transfections: Approximately 330 transfections/2 nmol in 24-well plate under optimized conditions (final conc. 10 nM).
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