SMPT (4-succinimidyloxycarbonyl-alpha-methyl-α(2-pyridyldithio)toluene), Pierce™

Lieferant: Thermo Fisher Scientific

Synonyme: 4-succinimidyloxycarbonyl-alpha-methyl-alpha-(2-pyridyldithio)toluene, SMPT, 2,5-Dioxopyrrolidin-1-yl 4-(1-(pyridin-2-yldisulphaneyl)ethyl)benzoate

21558
PIER21558EA 381 EUR
PIER21558
SMPT (4-succinimidyloxycarbonyl-alpha-methyl-α(2-pyridyldithio)toluene), Pierce™
SMPT (4-succinimidyloxycarbonyl-alpha-methyl-α(2-pyridyldithio)toluene)

Thermo Scientific Pierce SMPT is a long-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form strong (hindered) yet cleavable (reducible) disulfide bonds with cysteine sulfhydryls..


  • Reactive groups: NHS ester and pyridyldithiol
  • Reactive towards: amino and sulfhydryl groups
  • Cleavable with disulfide reducing agents
  • Water-insoluble (dissolve first in DMF or DMSO)
  • Contains a hindered disulfide bond; has formed immunotoxins with improved stability
  • In vitro, an SMPT conjugate was as effective as conjugates formed with SPDP and 2-IT
  • Compare to other varieties of SPDP-type reagents, including pegylated forms


Bitte beachten For Research Use Only. Not for use in diagnostic procedures.

Formel: C₁₈H₂₀N₂O₂S₂
Molecular Weight: 360,49 g/mol
Lagertemperatur: Kühlschrank
MDL: MFCD00083161
CAS-Nummer: 112241-19-7

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