MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride), Pierce™

Lieferant: Thermo Fisher Scientific

Synonyme: MPBH

22305
PIER22305EA 464 EUR
PIER22305
MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride), Pierce™
MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride)

Thermo Scientific Pierce MPBH is a long, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).


  • Reactive groups: maleimide and hydrazide
  • Reactive towards: sulfhydryl groups and carbonyl (aldehyde) groups
  • Long (17.9A), sulfhydryl-to-aldehyde crosslinker with an aromatic ring in its spacer arm (noncleavable)
  • Maleimide group reacts with sulfhydryl groups to form stable thioether linkages
  • Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates
  • Use sodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups
  • Use with EDC to conjugate primary amine of hydrazide group to carboxyl groups


Related Products, BMPH, EMCH, KMUH


Bitte beachten For Research Use Only. Not for use in diagnostic procedures.

Bestellen

Spezifikation Testergebnisse

Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Amine, Hydrazide, Maleimide
Spacer Long
Form Powder
Quantity 50 mg
Type Crosslinker
Solubility DMF, DMSO

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR