SBAP (Succinimidyl 3-(bromoacetamido)propionate), Pierce™
Lieferant: Thermo Fisher Scientific
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Achtung
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Synonyme:
SBAP
22339
PIER22339EA
206
EUR
PIER22339
SBAP (Succinimidyl 3-(bromoacetamido)propionate), Pierce™
SBAP (Succinimidyl 3-(bromoacetamido)propionate)
Thermo Scientific Pierce SBAP is a short (6.2 angstrom) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and bromoacetyl reactive groups.
- Reactive groups: NHS ester and bromoacetyl
- Reactive toward: amino and sulfhydryl groups
- NHS ester reacts with primary amines at pH 7-9 to form a stable amide bond
- Bromacetyl group reacts with sulfhydryl groups at pH > 7.5 to form stable thioether bonds
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO)
- Spacer maintains peptide-like character in the crosslinked species
- Resulting crosslink is susceptible to acid hydrolysis
- Useful for preparing cyclic peptides and peptide conjugates
Bitte beachten For Research Use Only. Not for use in diagnostic procedures.
Formel:
C₉H₁₁BrN₂O₅ Molecular Weight: 307,098 g/mol Lagertemperatur: Gefrierschrank |
MDL:
MFCD01863457 CAS-Nummer: 57159-62-3 |
Spezifikation Testergebnisse
Product Line | Pierce™ |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Reactive Moiety | Haloacetyl, NHS Ester |
Spacer | Short |
Form | Solid |
Quantity | 50 mg |
Type | Crosslinker |
Solubility | DMF, DMSO |
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