PMPI (4-Maleimidophenyl isocyanate), Pierce™

Lieferant: Thermo Fisher Scientific
Gefahr

Synonyme: PMPI

28100
PIER28100EA 245 EUR
PIER28100
PMPI (4-Maleimidophenyl isocyanate), Pierce™
PMPI (4-Maleimidophenyl isocyanate)

Thermo Scientific Pierce PMPI is a maleimide-and-isocyanate crosslinker for attaching compounds to sulfhydryl groups (cysteines) after conjugating the linker to hydroxyl groups on a molecule by urethane (carbamate) bonds.


  • Reactive groups: maleimide and isocyanate
  • Reactive towards: sulfhydryl and hydroxyl groups
  • Short (8.7A), sulfhydryl-to-hydroxyl crosslinker with an aromatic spacer arm (noncleavable)
  • Maleimide group reacts with sulfhydryl groups to form stable thioether linkages
  • Isocyanate reacts with non-aqueous hydroxyl groups to form carbamate linkage
  • Excellent tool for conjugating hydroxyl-containing compounds such as steroids and vitamins
  • Targets and reaction solutions must not contain primary amines


Bitte beachten For Research Use Only. Not for use in diagnostic procedures.

Formel: C₁₁H₆N₂O₃
Molecular Weight: 214,177 g/mol
Schmelzpunkt: 121…123°C
Lagertemperatur: Kühlschrank
MDL: MFCD00270900
CAS-Nummer: 123457-83-0

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Spezifikation Testergebnisse

Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Maleimide, Isocyanate
Spacer Short
Form Solid
Quantity 50 mg
Type Crosslinker
Solubility DMF, DMSO

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