PMPI (4-Maleimidophenyl isocyanate), Pierce™
Lieferant: Thermo Fisher Scientific
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Gefahr
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Synonyme:
PMPI
28100
PIER28100EA
245
EUR
PIER28100
PMPI (4-Maleimidophenyl isocyanate), Pierce™
PMPI (4-Maleimidophenyl isocyanate)
Thermo Scientific Pierce PMPI is a maleimide-and-isocyanate crosslinker for attaching compounds to sulfhydryl groups (cysteines) after conjugating the linker to hydroxyl groups on a molecule by urethane (carbamate) bonds.
- Reactive groups: maleimide and isocyanate
- Reactive towards: sulfhydryl and hydroxyl groups
- Short (8.7A), sulfhydryl-to-hydroxyl crosslinker with an aromatic spacer arm (noncleavable)
- Maleimide group reacts with sulfhydryl groups to form stable thioether linkages
- Isocyanate reacts with non-aqueous hydroxyl groups to form carbamate linkage
- Excellent tool for conjugating hydroxyl-containing compounds such as steroids and vitamins
- Targets and reaction solutions must not contain primary amines
Bitte beachten For Research Use Only. Not for use in diagnostic procedures.
Formel:
C₁₁H₆N₂O₃ Molecular Weight: 214,177 g/mol Schmelzpunkt: 121…123°C Lagertemperatur: Kühlschrank |
MDL:
MFCD00270900 CAS-Nummer: 123457-83-0 |
Spezifikation Testergebnisse
Product Line | Pierce™ |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Reactive Moiety | Maleimide, Isocyanate |
Spacer | Short |
Form | Solid |
Quantity | 50 mg |
Type | Crosslinker |
Solubility | DMF, DMSO |
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