Human Recombinant TH17 Cell Polarizing Plus PB (from E. coli)

Lieferant: Shenandoah Biotechnology

PB-500-12
SHBTPB-500-12EA 917 EUR
SHBTPB-500-12
Human Recombinant TH17 Cell Polarizing Plus PB (from E. coli)
Proteine und Peptide

Cytokines for polarizing human T cells into Th9 cells. Th9 cells are a unique subset of T helper cells that produce IL-9. An important function of IL-9 producing T cells is fighting inflammation and helminth infections. Th9 cells can be generated from naive CD4+ T cells in culture by culturing them in the presence of IL-4 and TGF-β 1. It also appears that IFNγ and IL-27 can inhibit the generation of Th9 cells.


  • High quality
  • Low endotoxin
  • Affordable


Th17 cells are characterized by their ability to produce IL-17, IL-22 and IL-21. Th17 cells can be cultured from naive CD4+ T cells by culturing them in the presence of anti-CD3 and anti-CD28 stimulation with recombinant IL-6 and recombinant TGF-β 1. In some cases neutralizing antibodies against IL-12, IL-4 and IFNγ are used along with recombinat cytokines IL-1 β, IL-21 and/or IL-23.


Bitte beachten For research use only.

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