Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) PEG ∽Mn 5,000, PLGA ∽Mn 7,000, Sigma-Aldrich®
Lieferant: Merck
Synonyme:
mPEG-b-PLGA, PEG-PLGA
Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic.
- Feed ratio lactide:glycolide 50:50
- Good biocompatibility, low immunogenicity and good degradability.
- Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.
These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.
Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...