SBAP (Succinimidyl 3-(bromoacetamido)propionate) ≥90%, Sigma-Aldrich®

Lieferant: Merck
Achtung

Synonyme: SBAP

M-Clarity™ Qualitätsstufe = MQ100

803650-50MG
SIAL803650-50MGEA 245 EUR
SIAL803650-50MG
SBAP (Succinimidyl 3-(bromoacetamido)propionate) ≥90%, Sigma-Aldrich®
SBAP (Succinimidyl 3-(bromoacetamido)propionate)

SBAP is a sulfhydryl-reactive and amine-reactive heterobifunctional crosslinker. The reagent′s NHS ester reacts with primary amines at pH 7-9 to form stable amide bonds, and the bromacetyl reacts with sulfhydryl groups at pH >7.5 to form stable thioether bonds This reagent is useful for preparing cyclic peptides and peptide conjugates because the spacer maintains peptide-like character in the crosslinked species.


  • Reactive groups: NHS ester and bromoacetyl
  • Reactive toward: amino and sulfhydryl groups
  • NHS ester reacts with primary amines at pH 7-9 to form a stable amide bond
  • Bromacetyl group reacts with sulfhydryl groups at pH > 7.5 to form stable thioether bonds
  • Non-cleavable
  • Water-insoluble (dissolve first in DMF or DMSO)
  • Spacer maintains peptide-like character in the crosslinked species
  • Resulting crosslink is susceptible to acid hydrolysis
  • Useful for preparing cyclic peptides and peptide conjugates


This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.

Formel: C₉H₁₁BrN₂O₅
Molecular Weight: 307,098 g/mol
Lagertemperatur: Kühlschrank
MDL: MFCD01863457
CAS-Nummer: 57159-62-3

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