Brefeldin A 10 mg/ml in DMSO (aus Penicillium brefeldianum) ≥98,00% (durch HPLC) anwendungsbereit, Sigma-Aldrich®

Lieferant: Merck

Synonyme: (1R,2E,6S,10E,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-6,7,8,9,12,13,14,14a-octahydro-1H-cyclopenta[f][1]oxacyclotridecin-4(11aH)-one, Brefeldin A, natural

M-Clarity™ Qualitätsstufe = MQ200

B5936-200UL
SIALB5936-200ULEA 208 EUR
SIALB5936-200UL
Brefeldin A 10 mg/ml in DMSO (aus Penicillium brefeldianum) ≥98,00% (durch HPLC) anwendungsbereit, Sigma-Aldrich®
Brefeldin A

Brefeldin A produced from Penicillium brefeldianum may be used to study protein and lipid transport between Golgi complex and the cell surface.


Brefeldin A (BFA) is a fungal metabolite which disrupts the structure and function of the Golgi apparatus by inhibiting transport of proteins from ER to Golgi and inducing retrograde protein transport from the Golgi apparatus to the endoplasmic reticulum. BFA inhibits the transport of sphingomyelin to the surface of mammalian cells. The ester derivatives of BFA exhibit anti-cancer properties.


Hygroscopic. Soluble in DMSO (10 mg/ml).


Sterility: 0,2 μm filtered


Bitte beachten Store under inert gas. Storage class (TRGS 510): Combustible liquids

Formel: C₁₆H₂₄O₄
Molecular Weight: 280,4 g/mol
Lagertemperatur: Kühlschrank
MDL: MFCD00083258
CAS-Nummer: 20350-15-6

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Spezifikation Testergebnisse

Concentration 10.000 - 10.500 mg/ml
Purity (HPLC) ≥98.00%
Vapor Pressure 0.56 hPa ( 20 °C)
Autoignition Temperature 301 °C
Antibiotic Activity Spectrum Neoplastics

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