JC-1 (iodide), Sigma-Aldrich®
Lieferant: SIGMA ALDRICH MICROSCOPY
Synonyme:
JC1, 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide, 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide, 5,5’,6,6’-Tetrachloro-1,1’,3,3’-tetraethylbenzimidazolylcarbocyanine iodide
A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent (λex 520 nm) monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent (λem 596 nm ) "J-aggregates," which exhibit broad excitation and very narrow emission spectra. The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by mitochondrial size, shape, or density.
Formel:
C₂₅H₂₇Cl₄IN₄ Molecular Weight: 652,223 g/mol Lagertemperatur: Raumtemperatur |
MDL:
MFCD00188475 CAS-Nummer: 3520-43-2 |
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