Sie suchten nach: 3-(2,5-Difluorophenyl)-1H-pyrazole


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Beschreibung: A cell permeable, highly specific, potent and ATP-competitive inhibitor of Rho kinase (ROCK) (Ki=1.6nM). Exhibits a much weaker affinity for other serine/threonine kinases (Ki=630nM for PKA, 9.27mM for PKC and 10.1mM for MLCK). More potent and selective than Y-27632. Inhibits the phosphorylation of MARCKS in cells stimulated by lysophosphatidic acid. Inhibits EP3-stimulated NO formation. Prevents fragmentation of apoptotic cells. Relieves neuropathic pain.
Artikel-Nr: ENZOALX270423M005
VE: 1 * 5 mg
Lieferant: ENZO LIFE SCIENCES

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