Anti-FN1 Mouse Monoclonal Antibody (CF405S) [clone: TV-1]

Lieferant: Biotium

BNC040029-500EA 530 EUR
BNC040029-500 BNC040029-100
Anti-FN1 Mouse Monoclonal Antibody (CF405S) [clone: TV-1]
Antikörper
Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.

Type: Primary
Antigen: FN1
Clonality: Monoclonal
Clone: TV-1
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Mouse, Pig, Rat
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