Benzo[a]pyren ≥96% (durch HPLC), Sigma-Aldrich®
Lieferant: Merck
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Gefahr
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Synonyme:
Benzo[def]chrysen, BaP
M-Clarity™ Qualitätsstufe = MQ200
Benzo[a]pyrene (PAH), a polycyclic aromatic hydrocarbon pollutant, is used as a chemical carcinogen in experimental models of cancer.
Carcinogenesis depends on it′s oxidation by CYP1A1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with DNA that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (AhR), and some of its biological effects, including the induction of CYP1A1, appear to be mediated via activation of the AhR.
Formel:
C₂₀H₁₂ Molecular Weight: 252,32 g/mol Siedepunkt: 495 °C (1013 hPa) Schmelzpunkt: 176…178 °C Dichte: 1,351 g/cm³ (20 °C) |
MDL:
MFCD00003602 CAS-Nummer: 50-32-8 EINECS: 200-028-5 UN: 2811 ADR: 6.1,III Merck Index: 12,01134 |
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