EPZ-5676 (Pinometostat) ≥98%
Lieferant: Cayman Chemical
EPZ5676 is a highly potent aminonucleoside inhibitor of DOT1 l histone methyltransferase activity (Ki = 80 pM) that demonstrates 37000-fold selectivity over other methyltransferases.
It can selectively inhibit the proliferation of acute leukemia cell lines bearing MLL translocations (IC50s range from 3.5 nM - 1.3 µM).
Formel:
C₃₀H₄₂N₈O₃ Lagertemperatur: Gefrierschrank |
MDL:
MFCD24849415 CAS-Nummer: 1380288-87-8 |
Spezifikation Testergebnisse
Purity | ≥98% |
Formulation | A Crystalline Solid |
λmax | 255 nm |
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