N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

Lieferant: Apollo Scientific

Synonyme: Gefitinib

BISN0101-1G BISN0101-5G
APOSBISN0101-1GEA 139 EUR
APOSBISN0101-1G APOSBISN0101-5G
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

Gefitinibis an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively, and interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.

Formel: C₂₂H₂₄ClFN₄O₃
Molecular Weight: 446,91 g/mol
Schmelzpunkt: 196 °C
Lagertemperatur: Kühlschrank
MDL: MFCD04307832
CAS-Nummer: 184475-35-2

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