Dexamethason, weißes Pulver

Lieferant: MP Biomedicals
Gefahr

Synonyme: 9-Fluor-11β,17α,21-trihydroxy-16α-methyl-pregna-1,4-dien-3,20-dion, Dexamethasonum

0219004094 0219004025 0219004080 0219004090 0219004091
ICNA0219004094EA 1015 EUR
ICNA0219004094 ICNA0219004025 ICNA0219004080 ICNA0219004090 ICNA0219004091
Dexamethason, weißes Pulver
Dexamethason

Dexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin).


It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein. Dexamethasone has been observed to induce apoptosis in human thymocytes and eosinophils but to inhibit apoptosis in neutrophils.


Dexamethasone is a glucocorticoid anti-inflammatory agent. It regulates T cell survival, growth, and differentiation. It also inhibits the induction of nitric oxide synthase.


Slightly soluble in water (10 mg/100 ml), ethanol (1 mg/ml), chloroform; sparingly soluble in acetone, alcohol, dioxane, and methanol; very slightly soluble in ether

Formel: C₂₂H₂₉FO₅
Molecular Weight: 392,47 g/mol
Schmelzpunkt: 262…264 °C (Lit.)
MDL: MFCD00064136
CAS-Nummer: 50-02-2
EINECS: 200-003-9

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Spezifikation Testergebnisse

Identity Test Passes
FTIR Conforms to Standard C
Loss on Drying ≤5,0%
Optical Rotation +72 ° to +80 ° (c=1, dioxane)

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