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Artikel-Nr: (BOSSBS-5164R-FITC)
Lieferant: Bioss
Beschreibung: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-11676R-A350)
Lieferant: Bioss
Beschreibung: UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1 to 2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p14. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.
VE: 1 * 100 µl


Lieferant: Biotium
Beschreibung: Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

Lieferant: Biotium
Beschreibung: Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

Lieferant: VWR Chemicals
Beschreibung: Alle unsere Nährmedien werden aus hochwertigen Rohstoffen hergestellt und unterliegen strengen Qualitätskontrollen; bei der Produktion kommen die aktuellen Good Manufacturing Practice-Richtlinien (GMP) zur Anwendung. Die Rohstoffe werden entsprechend den erforderlichen Standards ausgewählt. Trockennährmedien sollten, sofern nicht anders angegeben, bei 10 bis 30 °C in ihren verschlossenen Behältern in trockener Umgebung aufbewahrt werden. Eine Reihe an Nährmedien ist gemäß ISO-Normen und der international harmonisierten Pharmakopöe.
Lieferant: Biotium
Beschreibung: Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

Lieferant: Biotium
Beschreibung: Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

Lieferant: Merck
Beschreibung: Trockennährböden werden für eine Vielzahl von Anwendungen benötigt. Um die mit pulverförmigen Nährböden verbundenen Risiken zu minimieren, werden die meisten Trockennährböden von Merck in Granulatform hergestellt. Um das potentielle Risiko einer Übertragung transmissibler spongiformer Enzephalopathien (TSE) einzudämmen, verwendet Merck Grundstoffe nicht tierischen Ursprungs. Wenn dies nicht möglich ist, werden nur Substanzen eingesetzt, die vom EDQM empfohlen werden und den TSE-Kategorien B oder C angehören. Somit wird gewährleistet, dass das Produkt von höchster Qualität ist und den Standards für die Lebensmittelkontrolle, die mikrobiologische Untersuchung von Endprodukten und Rohstoffen oder die Qualitätskontrolle in der Pharma- und Kosmetikindustrie entspricht. Spezielle Nährböden können nach kundenspezifischen Vorgaben hergestellt werden. Die Zusammensetzung wird im Rahmen einer Geheimhaltungsvereinbarung vertraulich behandelt. Vorteile der granulierten Medien von Merck.
Artikel-Nr: (85879.0500)
Lieferant: VWR Chemicals
Beschreibung: Granulierte Trockennährmedien von VWR® bieten dem Anwender viele Vorteile und mehr Sicherheit. Für eine optimale Leistung ist eine vollständige Auflösung der Nährmedien unerlässlich. Granulierte Nährmedien sind einfacher bei der Zubereitung und sparen Zeit. Darüber hinaus wird die Stauberzeugung durch die Granulierung reduziert und die Handhabung wird angenehmer und sicherer für den Anwender. Dies sorgt für eine wesentlich sauberere und sicherere Arbeitsumgebung.
VE: 1 * 500 g

Zertifikate


Artikel-Nr: (BOSSBS-5164R-CY5.5)
Lieferant: Bioss
Beschreibung: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
VE: 1 * 100 µl


Artikel-Nr: (710-0742)
Lieferant: DOEHLER GROUP
Beschreibung: The concentrated LMC broth is based on Lactose-Peptone broth as described in the German Drinking Water Regulation (DEV, DIN 38411) and the Mineral- and Table Water Regulation (MwTVO) for the analysis of E.coli and coliform bacteria in water. LMC is 10-fold concentrated and a sample quantity of 250 mL water can be added directly into the original bottle. After mixing with the water sample, the broth attains the required concentration (double concentrated) and is ready for immediate incubation.
VE: 1 * 9 ST

Zertifikate


Lieferant: LIOFILCHEM
Beschreibung: The peelable blister pack fulfills the highest quality and protection standards for the plate. The blister pack, produced fully automatically and in controlled environment, offers the following advantages compared to the pouch pack:

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Lieferant: Biotium
Beschreibung: Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

Lieferant: Biotium
Beschreibung: Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

Lieferant: CHROMAGAR
Beschreibung: Chromogenic technology applied to culture media allows you to differentiate and easily identify, inside one single plate, the growth of different microorganisms.
Artikel-Nr: (BOSSBS-11676R-CY7)
Lieferant: Bioss
Beschreibung: UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1 to 2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p14. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.
VE: 1 * 100 µl


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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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