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Image Unavailable-BOSSBS-11825R-A488

Anti-DOCK7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-11825R-A488)
Lieferant: Bioss
Beschreibung: DOCK 7 is a 2,140 amino acid protein that localizes to developing axons and contains one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues, DOCK 7 functions as a guanine nucleotide exchange factor (GEF) that specifically activates Rac 1 and Rac 3 by catalyzing the exchange of bound GDP for free GTP. Multiple isoforms of DOCK 7 exist due to alternative splicing events.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-10955R-A750

Anti-Epac2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-10955R-A750)
Lieferant: Bioss
Beschreibung: Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).
VE: 1 * 100 µl
Image Unavailable-BOSSBS-11825R-A647

Anti-DOCK7 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-11825R-A647)
Lieferant: Bioss
Beschreibung: DOCK 7 is a 2,140 amino acid protein that localizes to developing axons and contains one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues, DOCK 7 functions as a guanine nucleotide exchange factor (GEF) that specifically activates Rac 1 and Rac 3 by catalyzing the exchange of bound GDP for free GTP. Multiple isoforms of DOCK 7 exist due to alternative splicing events.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-11825R-A350

Anti-DOCK7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-11825R-A350)
Lieferant: Bioss
Beschreibung: DOCK 7 is a 2,140 amino acid protein that localizes to developing axons and contains one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues, DOCK 7 functions as a guanine nucleotide exchange factor (GEF) that specifically activates Rac 1 and Rac 3 by catalyzing the exchange of bound GDP for free GTP. Multiple isoforms of DOCK 7 exist due to alternative splicing events.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-8254R-A555

Anti-DENND1B Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-8254R-A555)
Lieferant: Bioss
Beschreibung: Guanine nucleotide exchange factor (GEF) for RAB35. May function as a clathrin-associated sorting protein for RAB35, whereby during clathrin-mediated endocytosis, binds the AP-2 complex and inactived RAB35, then activates RAB35 for its subsequent function at endosomes.Tissue specificity:Highly expressed in dendritic and natural killer cells and at lower levels in other myeloid lineage cells and in pituitary. Significantly up-regulated in effector memory T cells as compared with naive T cells.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-8254R-A350

Anti-DENND1B Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-8254R-A350)
Lieferant: Bioss
Beschreibung: Guanine nucleotide exchange factor (GEF) for RAB35. May function as a clathrin-associated sorting protein for RAB35, whereby during clathrin-mediated endocytosis, binds the AP-2 complex and inactived RAB35, then activates RAB35 for its subsequent function at endosomes.Tissue specificity:Highly expressed in dendritic and natural killer cells and at lower levels in other myeloid lineage cells and in pituitary. Significantly up-regulated in effector memory T cells as compared with naive T cells.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-6162R-A647

Anti-ARL3 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-6162R-A647)
Lieferant: Bioss
Beschreibung: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for normal cytokinesis and cilia signaling.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-6162R

Anti-ARL3 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-6162R)
Lieferant: Bioss
Beschreibung: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for normal cytokinesis and cilia signaling.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-6162R-CY5

Anti-ARL3 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-6162R-CY5)
Lieferant: Bioss
Beschreibung: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for normal cytokinesis and cilia signaling.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-3680R-A750

Anti-Adenomatous Polyposis Coli Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-3680R-A750)
Lieferant: Bioss
Beschreibung: Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-6162R-A680

Anti-ARL3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-6162R-A680)
Lieferant: Bioss
Beschreibung: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for normal cytokinesis and cilia signaling.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-2936R

Anti-ARHGEF7 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-2936R)
Lieferant: Bioss
Beschreibung: ARHGEF7 is a p21-activated protein kinase (Pak)-interacting exchange factor that has been identified as a putative guanine nucleotide exchange factor (GEF) for Rac/Cdc42. It is expressed ubiquitously in all the tissue examined and other isoforms are expressed mainly in the central nervous system. Regulated phosphorylation of ARHGEF7 is necessary to maintain the balance between normal signalling by EGFR and Src versus aberrant growth and transformation.Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene, but some of their full-length sequences have not been determined.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-12431R-CY5

Anti-DOCK2 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-12431R-CY5)
Lieferant: Bioss
Beschreibung: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-7144R-A350

Anti-ARHGEF18 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-7144R-A350)
Lieferant: Bioss
Beschreibung: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].
VE: 1 * 100 µl
Image Unavailable-BOSSBS-11459R-CY5

Anti-FARP2 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-11459R-CY5)
Lieferant: Bioss
Beschreibung: FARP2 is a 1,545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-10466R-CY7

Anti-RHOG Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-10466R-CY7)
Lieferant: Bioss
Beschreibung: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011].
VE: 1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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