Sie suchten nach: Rosiglitazone

38 Ergebnisse wurden gefunden

Suchergebnis einschränken: Sortieren nach

Sort Results

Listenansicht Hybridansicht

Vergleichen(0) Entfernen

Bewerten Sie das Suchergebnis

Rosiglitazone maleate

Artikel-Nr: (ACRO462410010)

Lieferant: Thermo Scientific

Beschreibung: Rosiglitazone maleate

VE: 1 * 1 g

Sale!

N/A Each

Rosiglitazone ≥97% (durch HPLC)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Insulin sensitising agent.

Neuer Artikel bei VWR!

Beschreibung: Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions <italic>in vivo</italic>. Rosiglitazone is a prototypical TZD and has served as a reference compound for this class. Rosiglitazone is a potent and selective PPARγ ligand. It binds to the PPARγ ligand-binding domain with a Kd of 43 nM. It activates luciferase-based expression constructs PPARγ1 and PPARγ2 with EC<sub>50</sub> values of approximately 30 nM and 100 nM, respectively. Rosiglitazone is active <italic>in vivo</italic> as an antidiabetic agent in the <italic>ob/ob</italic> mouse model, and has been used as an oral hypoglycemic agent in the treatment of Type II diabetes in humans for many years.

Rosiglitazone Related Compounds, Reference Standard

Lieferant: USP

Beschreibung: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.