Sie suchten nach: VITAL+SCIENTIFIC

Artikel-Nr: (PRSI96-367)

Lieferant: ProSci Inc.

Beschreibung: Human Immunodeficiency Virus (HIV) can be divided into two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is related to viruses found in chimpanzees and gorillas living in western Africa. HIV-2 is related to viruses found in sooty mangabeys. HIV-1 viruses may be further divided into groups. The HIV-1 group M viruses predominate and are responsible for the AIDS pandemic. Some of the HIV-1 group M subtypes are known to be more virulent or are resistant to different medications. HIV-2 viruses are thought to be less virulent and transmissible than HIV-1 M group viruses.
Envelope glycoprotein GP120 (or gp120) is the name of the glycoprotein which forms the spikes sticking out of a HIV virus particle. gp120 is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry. Three gp120s, bound as heterodimers to a transmembrane glycoprotein, gp41, are thought to combine in a trimer to form the envelope spike, which is involved in virus-cell attachment. One half of the molecular weight of gp120 is due to the carbohydrate side chains (the "glyco-" in "glycoprotein"). These are sugar residues which form something almost like a sugar "dome" over the gp120 spikes. This dome prevents gp120 from being recognised by the human immune response. As the HIV virus and the human CD4 cell come together, the gp120 binding site "snaps open" at the last minute.The glycoprotein gp120 is anchored to the viral membrane, or envelope, via non-covalent bonds with the transmembrane glycoprotein, gp41. It is involved in entry into cells by binding to CD4 receptors, particularly helper T-cells. Binding to CD4 is mainly electrostatic although there are van der Waals interactions and hydrogen bonds.

VE: 1 * 100 µG

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Artikel-Nr: (PRSI33-250)

Lieferant: ProSci Inc.

Beschreibung: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

VE: 1 * 100 µG

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Artikel-Nr: (PRSI96-365)

Lieferant: ProSci Inc.

Beschreibung: Human Immunodeficiency Virus (HIV) can be divided into two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is related to viruses found in chimpanzees and gorillas living in western Africa. HIV-2 is related to viruses found in sooty mangabeys. HIV-1 viruses may be further divided into groups. The HIV-1 group M viruses predominate and are responsible for the AIDS pandemic. Some of the HIV-1 group M subtypes are known to be more virulent or are resistant to different medications. HIV-2 viruses are thought to be less virulent and transmissible than HIV-1 M group viruses.
Envelope glycoprotein GP120 (or gp120) is the name of the glycoprotein which forms the spikes sticking out of a HIV virus particle. gp120 is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry. Three gp120s, bound as heterodimers to a transmembrane glycoprotein, gp41, are thought to combine in a trimer to form the envelope spike, which is involved in virus-cell attachment. One half of the molecular weight of gp120 is due to the carbohydrate side chains (the "glyco-" in "glycoprotein"). These are sugar residues which form something almost like a sugar "dome" over the gp120 spikes. This dome prevents gp120 from being recognised by the human immune response. As the HIV virus and the human CD4 cell come together, the gp120 binding site "snaps open" at the last minute.The glycoprotein gp120 is anchored to the viral membrane, or envelope, via non-covalent bonds with the transmembrane glycoprotein, gp41. It is involved in entry into cells by binding to CD4 receptors, particularly helper T-cells. Binding to CD4 is mainly electrostatic although there are van der Waals interactions and hydrogen bonds.

VE: 1 * 100 µG

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Artikel-Nr: (521-4268)

Lieferant: Thermo Scientific

Beschreibung: Zentrifuge, Tischmodell, SECURE-Spin, advanced user management and centralised monitoring features on Thermo Scientific general purpose pro centrifuges, for 1,6 and 4 L capacities, maximum 25830×g

VE: 1 * 1 ST

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Artikel-Nr: (HERA75003837)

Lieferant: Thermo Scientific

Beschreibung: Thermo Scientific™ Blutbankzentrifugen bieten die Flexibilität, Rotoren mit höherer Kapazität auszuwählen oder vorhandene Arbeitsabläufe anzupassen, mit einer Auswahl an Thermo Scientific™ HAEMAFlex™ Rotoren und Bechersystemen.

VE: 1 * 2 ST

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Lieferant: Thermo Scientific

Beschreibung: Thermo Scientific-Blutbankzentrifugen bieten die Flexibilität, Rotoren mit höherer Kapazität auszuwählen oder vorhandene Arbeitsabläufe anzupassen, mit einer Auswahl an Thermo Scientific™ HAEMAFlex™-Rotoren und Bechersystemen.

Artikel-Nr: (HERA75100378)

Lieferant: Thermo Scientific

Beschreibung: Integrieren Sie Thermo Scientific™ Fiberlite™ Rotoradapter mit Fiberlite F13-14x50c- und F15-8x50c-Rotoren.

VE: 1 * 2 ST

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Lieferant: SORVALL

Beschreibung: Process a 16 L harvest in a single run with the Thermo Scientific™ 2000 ml bottle, the ideal solution for the separation of large volume harvests. Designed for use in Thermo Scientific™ Sorvall™ BIOS 16 Bioprocessing Centrifuge and 6 x 2000 ml or 8 x 2000 ml Swing Bucket Rotor.

Lieferant: VWR Collection

Beschreibung: Die Flaschen werden vorzugsweise für Geräte der folgenden Hersteller verwendet: Agilent, Dionex, Shimadzu, Tekmar, Thermo Scientific, Varian.

Artikel-Nr: (FD1464)

Lieferant: Thermo Fisher Scientific

Beschreibung: Thermo Scientific™ FastDigest™ enzymes are an advanced line of restriction enzymes for rapid DNA digestion.

VE: 1 * 1 KIT

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Lieferant: Thermo Scientific

Beschreibung: Für Blutverarbeitungsanforderungen mit hohem Durchsatz bietet der Thermo Scientific™ HAEMAFlex™ 12 Ausschwingrotor eine Kapazität von 12× 500 ml oder erweitern Sie Ihre Zentrifugenkapazität auf 16× 500 ml Blutbeutel mit dem Thermo Scientific™ HAEMAFlex™ 16 Rotor und derselben Becherauswahl.

Lieferant: Thermo Fisher Scientific

Beschreibung: Automated nucleic acid purification system, accessory, Thermo Scientific™ KingFisher™ Apex PCR Heizblock

Artikel-Nr: (818-0062)

Lieferant: VWR Collection

Beschreibung: Convenient pocket size calculator can handle 99% of all routine and other calculations in the laboratory. Provides immediate, exact results for a wide range of applications: Conversions, scientific calculations, statistical operations, arithmetic calculations and similar laboratory work. Display: 10 characters with two-digit exponent.

VE: 1 * 1 ST

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Lieferant: Thermo Fisher Scientific

Beschreibung: The Thermo Scientific Thermal Mixer offers variable speed and temperature control with a choice of blocks for microtubes and microplates.

Lieferant: Trajan Scientific and Medical

Beschreibung: * gasdicht

Artikel-Nr: (NALG362515-0480)

Lieferant: Thermo Fisher Scientific

Beschreibung: Protect the contents in your Thermo Scientific™ Biotainer™ bottles and carboys. Thermo Scientific™ Nalgene™ sterile polypropylene biotainer replacement closures are for 1, 2, 5, 10 and 20 L polycarbonate biotainers.

VE: 1 * 300 ST

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