Sie suchten nach: E3 Cortex

Artikel-Nr: (PRSI29-552)

Lieferant: ProSci Inc.

Beschreibung: WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene.

VE: 1 * 100 µG

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Artikel-Nr: (PRSI38-304)

Lieferant: ProSci Inc.

Beschreibung: Anti-IL22 Rabbit Polyclonal Antibody

VE: 1 * 100 µG

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Artikel-Nr: (PRSI45-889)

Lieferant: ProSci Inc.

Beschreibung: Anti-MLH3 Goat Polyclonal Antibody

VE: 1 * 100 µG

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Artikel-Nr: (PRSI92-390)

Lieferant: ProSci Inc.

Beschreibung: Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signalling induced by ConA, which probably includes Src family tyrosine-protein kinases.

VE: 1 * 50 µG

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Artikel-Nr: (PRSI92-377)

Lieferant: ProSci Inc.

Beschreibung: D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyse D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine.

VE: 1 * 50 µG

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Artikel-Nr: (PRSI1608)

Lieferant: ProSci Inc.

Beschreibung: Immunoblotting: 1/1000 - 1/20000, ELISA: 1/1000 - 1/20000, Immunohistochemistry: 1/100 - 1/1000

VE: 1 * 0,5 mg

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Artikel-Nr: (PRSI96-884)

Lieferant: ProSci Inc.

Beschreibung: Human Epidermal growth factor Receptor 2 (HER2), also called ERBB2, HER-2, HER-2/neu, NEU, NGL,TKR1 and c-erb B2,and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family.

VE: 1 * 25 µG

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Artikel-Nr: (PRSI10-877)

Lieferant: ProSci Inc.

Beschreibung: Anti-RG7716 Recombinant Antibody

VE: 1 * 0,1 mg

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Artikel-Nr: (PRSI99-737)

Lieferant: ProSci Inc.

Beschreibung: Anti-NP Mouse Monoclonal Antibody [clone: [3D7]] (HRP (Horseradish Peroxidase))

VE: 1 * 1 mL

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Artikel-Nr: (PRSI99-523)

Lieferant: ProSci Inc.

Beschreibung: Anti-SPN Mouse Monoclonal Antibody [clone: [DF-T1]]

VE: 1 * 0,1 mg

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Artikel-Nr: (PRSI25-224)

Lieferant: ProSci Inc.

Beschreibung: TRIM9 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.

VE: 1 * 50 µG

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Artikel-Nr: (PRSI25-226)

Lieferant: ProSci Inc.

Beschreibung: PHF17 belongs to the JADE family. It contains 2 PHD-type zinc fingers. PHF17 is a transcriptional coactivator which seems to act by promoting acetylation of nucleosomal histone H4 by HTATIP. PHF17 promotes apoptosis. Itmay act as a renal tumor suppressor.

VE: 1 * 50 µG

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Artikel-Nr: (PRSI27-869)

Lieferant: ProSci Inc.

Beschreibung: UBP1 is an important SF1-independent transcriptional activator stimulating P450scc expression in human placental JEG-3 cells, whereas LBP-9 modulates the action of UBP1, exerting both positive and negative effects

VE: 1 * 50 µG

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Artikel-Nr: (PRSI3501P)

Lieferant: ProSci Inc.

Beschreibung: Rheb peptide is used for blocking the activity of the Rheb antibody.

VE: 1 * 50 µG

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Artikel-Nr: (PRSI27-866)

Lieferant: ProSci Inc.

Beschreibung: Enhancer binding protein TFAP4 is a transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence, CAGCTG.

VE: 1 * 100 µG

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Artikel-Nr: (PRSI27-871)

Lieferant: ProSci Inc.

Beschreibung: The WNT family consists of sereval secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT8B is a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.

VE: 1 * 100 µG

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