Antibody glycosylation analysis – the common, the accurate and the smart way

The webinar will present methods to analyze glycosylation of antibodies. As glycosylation of the Fc region of a therapeutic antibody influences its mode of action, glycan patterns are frequently analyzed:

• In development to monitor success of Fc-optimization
• In upstream development to screen the influence of production conditions on glycosylation
• During manufacturing to monitor the process
• In the final product for quality control, stability testings and comparisons between production lots

HPLC-based methods are presented that analyze Fc glycosylation and its functional consequences. We compare them and clarify which method is suitable for which question.

For more information, please contact us at webinar@avantorsciences.com