Anti-Human CD4 Mouse Monoclonal Antibody [clone: SK3] (iFluor® 810)

Lieferant: AAT BIOQUEST
100420O1
AATB100420O1EA 1410 EUR
AATB100420O1
Anti-Human CD4 Mouse Monoclonal Antibody [clone: SK3] (iFluor® 810)
Antikörper
SK3 is an anti-human monoclonal antibody that recognizes the CD4 antigen. CD4 (alternatively called T4 or Leu3a) is a 55 kD member of the Ig superfamily that is located on the surface of cells such as macrophages, T cells and granulocytes. CD4 has been associated with important biological processes such as membrane organization, specifically fusion of virus membrane with host plasma membrane. Furthermore, it is involved with vital cellular pathways, for example, the T cell receptor signaling pathway, enzyme linked receptor protein signaling pathway and cytokine-mediated signaling pathway.

In some organisms, CD4 acts to positively regulate peptidyl-tyrosine phosphorylation, is an enhancer of transcription, DNA-templated and is a positive regulator of ERK1 and ERK2 cascade. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands such as MHC Class II, gp120, IL-16 and Lck. CD4 is a very popular antibody target, with over 180000 publications in the last decade. CD4 is commonly used in flow cytometry applications as a phenotypic marker for differentiation of cell types, especially in the study of immunology. This antibody was purified through affinity chromatography and conjugated to iFluor® 810 (ex/em = 811/822 nm).

Type:
Antigen: Human CD4
Clonality: Monoclonal
Clone: SK3
Conjugation: iFluor® 810
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR