Anti-TLR2 Mouse Monoclonal Antibody (Biotin) [clone: TLR2/221]

Lieferant: Biotium
BNCB0221-500 BNCB0221-100
BNCB0221-500EA 560 EUR
BNCB0221-500 BNCB0221-100
Anti-TLR2 Mouse Monoclonal Antibody (Biotin) [clone: TLR2/221]
Antikörper
This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Type: Primary
Antigen: TLR2
Clonality: Monoclonal
Clone: TLR2/221
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Dog, Human, Monkey
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