Anti-MUC5AC Mouse Monoclonal Antibody (Purified, BSA-free) [clone: 45M1]

Lieferant: Biotium
BNUM0031-50
BNUM0031-50EA 417 EUR
BNUM0031-50
Anti-MUC5AC Mouse Monoclonal Antibody (Purified, BSA-free) [clone: 45M1]
Antikörper
This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. The epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Type: Primary
Antigen: MUC5AC
Clonality: Monoclonal
Clone: 45M1
Conjugation: Purified, BSA-free
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Cat, Chicken, Hedgehog, Human, Monkey, Mouse, Pig, Rabbit, Rat
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