Anti-APP Mouse Polyclonal Antibody (Alexa Fluor® 750)

Lieferant: Bioss
BS-0112M-A750
BOSSBS-0112M-A750EA 890 EUR
BOSSBS-0112M-A750
Anti-APP Mouse Polyclonal Antibody (Alexa Fluor® 750)
Antikörper
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Type: Primary
Antigen: Amyloid Precursor Protein
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 381-480/770
Host: Mouse
Isotype: IgG
Reactivity: Rat
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