Anti-ESR2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Lieferant: Bioss
BS-0116R-A488
BOSSBS-0116R-A488EA 901 EUR
BOSSBS-0116R-A488
Anti-ESR2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antikörper
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ESR2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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