Anti-PBEF CT Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Lieferant: Bioss
BS-0273R-A680
BOSSBS-0273R-A680EA 890 EUR
BOSSBS-0273R-A680
Anti-PBEF CT Rabbit Polyclonal Antibody (Alexa Fluor® 680)
Antikörper
catalyses the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

Type: Primary
Antigen: PBEF CT
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 401-491/491
Host: Rabbit
Isotype: IgG
Reactivity: Human
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