Anti-SLC22A17 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Lieferant: Bioss
BS-0444R-A647
BOSSBS-0444R-A647EA 901 EUR
BOSSBS-0444R-A647
Anti-SLC22A17 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antikörper
Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity).

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: SLC22A17
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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