Anti-IgA Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Lieferant: Bioss
BS-0474R-A488
BOSSBS-0474R-A488EA 893 EUR
BOSSBS-0474R-A488
Anti-IgA Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antikörper
Human IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: IgA
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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