Anti-MSH2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Lieferant: Bioss
BS-0758R-A647
BOSSBS-0758R-A647EA 893 EUR
BOSSBS-0758R-A647
Anti-MSH2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Antikörper
Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alphaMore Product Information
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TECHNISCHE DATEN

Antigen-Symbol MSH2
Environmentally Preferable
Antigen-Name MutS Homolog 2
Antigen-Synonyme DNA mismatch repair protein Msh2|COCA1|FCC1|HNPCC|hMSH2|HNPCC1|LCFS2
Antikörper-Typ Primär
Klonalität Polyklonal
Konjugation Alexa Fluor® 647
Reaktivität Human,Mouse
Wirt Rabbit
Gen-ID 4436
Isotyp IgG
ImmunoChemie Yes
Immunogen 80-130/935
Form liquid
Reinigung Purified by Protein A
Konzentration 1 μg/μl
Kreuzadsorption No
Lagerungspuffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Lagertemperatur Store at 4°C for 12 months
Transporttemperatur 4°C

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